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Pharmaceutical grade HPMC
Pharmaceutical grade HPMC
Pharmaceutical grade HPMC
Pharmaceutical grade HPMC
Pharmaceutical grade HPMC
Pharmaceutical grade HPMC
Pharmaceutical grade HPMC
Pharmaceutical grade HPMC
Pharmaceutical grade HPMC
Pharmaceutical grade HPMC

Pharmaceutical grade HPMC

Pharmaceutical grade HPMC Hydroxypropyl methylcellulose is white or milky white, odorless, tasteless, fibrous powder or granule, weight loss on drying does not exceed 10%, soluble in cold water but not hot water, slowly in hot water Swelling, peptization, and forming a viscous colloidal solution, which becomes a solution when cooled, and becomes a gel when heated.


Pharmaceutical Grade Hydroxypropyl Methylcellulose (HPMC) is a specialized form of HPMC used in the pharmaceutical industry. HPMC is a water-soluble polymer derived from cellulose, and when applied to pharmaceutical formulations, it offers several essential benefits and applications.

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    Chemical Specification

    description2

    Specification

    HPMC 60

    ( 2910 )

    HPMC 65

     ( 2906 )

    HPMC 75

    ( 2208 )

    Gel temperature (℃)

    58-64

    62-68

    70-90

    Methoxy (WT%)

    28.0-30.0

    27.0-30.0

    19.0-24.0

    Hydroxypropoxy (WT%)

    7.0-12.0

    4.0-7.5

    4.0-12.0

    Viscosity(cps, 2% Solution)

    3, 5, 6, 15, 50, 100, 400,4000, 10000, 40000, 60000,100000,150000,200000

    Product Grade:

    description2

    Specification

    HPMC 60

    ( 2910 )

    HPMC 65

     ( 2906 )

    HPMC 75

    ( 2208 )

    Gel temperature (℃)

    58-64

    62-68

    70-90

    Methoxy (WT%)

    28.0-30.0

    27.0-30.0

    19.0-24.0

    Hydroxypropoxy (WT%)

    7.0-12.0

    4.0-7.5

    4.0-12.0

    Viscosity(cps, 2% Solution)

    3, 5, 6, 15, 50, 100, 400,4000, 10000, 40000, 60000,100000,150000,200000

    Application

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    Pharma Excipients Application

    Pharmaceutical Grade HPMC

    Dosage

    Bulk Laxative

    75K4000,75K100000

    3-30%

    Creams, Gels

    60E4000,75K4000

    1-5%

    Ophthalmic Preparation

    60E4000

    01.-0.5%

    Eye Drops Preparations

    60E4000

    0.1-0.5%

    Suspending Agent

    60E4000, 75K4000

    1-2%

    Antacids

    60E4000, 75K4000

    1-2%

    Tablets Binder

    60E5, 60E15

    0.5-5%

    Convention Wet Granulation

    60E5, 60E15

    2-6%

    Tablet Coatings

    60E5, 60E15

    0.5-5%

    Controlled Release Matrix

    75K100000,75K15000

    20-55%

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    Key Properties and Uses of Pharmaceutical Grade HPMC:

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    1. Binder:

    HPMC acts as a binder in pharmaceutical tablet formulations. It helps hold the active pharmaceutical ingredients (APIs) and excipients together to form a cohesive tablet that can be easily ingested.

    2. Disintegrant:

    In some cases, HPMC can be used as a disintegrant in tablets. It aids in the rapid breakdown of the tablet into smaller particles, allowing for the release and absorption of the drug in the digestive system.

    3. Coating Material:

    HPMC is used as a film-coating material for tablets and capsules, providing protection for the drug, improving taste masking, and controlling the release of the API.

    4. Sustained Release:

    In controlled-release formulations, HPMC can be employed to modulate the release of the drug over time, providing a prolonged therapeutic effect.

    5. Viscosity Modifier: 

    It serves as a viscosity modifier in liquid and semi-solid formulations, such as oral suspensions and topical gels, to control the consistency and flow properties.

    6. Gelling Agent:

    HPMC can be used as a gelling agent in the formulation of oral gels and mucilages for ease of administration.

    Applications of Pharmaceutical Grade HPMC:

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    Pharmaceutical Grade HPMC is widely used in various pharmaceutical dosage forms, including:

    1. Tablets:

    It is a key component in tablet formulations, ensuring the proper binding of ingredients and disintegration characteristics.

    2. Capsules:

    HPMC can be used for capsule formulations, both as a binder for the powder fill and as a component of the capsule shell for delayed or sustained release.

    3. Coated Tablets:

    Film coatings made from HPMC protect the tablet and control the release of the drug.

    4. Oral Suspensions: 

    In liquid formulations, HPMC can act as a viscosity modifier, stabilizing the suspension.

    5. Topical Gels and Creams:

    It is used in topical formulations to achieve the desired texture and consistency.

    6. Mucilages:

    HPMC can be used in the formulation of mucilages for oral administration.

    Advantages of Using Pharmaceutical Grade HPMC:

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    - Improved tablet binding and disintegration.
    - Controlled release of drugs for extended therapeutic effects.
    - Taste masking and protection of the drug in coated tablets.
    - Enhanced texture and consistency in liquid and semi-solid formulations.
    - Suitable for use in various pharmaceutical dosage forms.

    Pharmaceutical Grade HPMC plays a crucial role in the pharmaceutical industry, contributing to the quality and performance of various drug formulations. Its properties make it a versatile and widely used excipient in tablet manufacturing, controlled-release formulations, and other pharmaceutical applications, ensuring that medications are effective, stable, and safe for patients.

    Packaging

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    The standard packing is 25kg/Fibre drum 
    20’FCL: 9 ton with palletized; 10 ton unpalletized.
    40’FCL: 18 ton with palletized; 20 ton unpalletized.

    Storage:

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    Store it in a cool, dry place below 30°C and protected against humidity and pressing, since the goods is thermoplastic, storage time should not exceed 36 months.

    Safety notes:

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    The above data is in accordance with our knowledge, but don’t absolve the clients carefully checking it all immediately on receipt. To avoid the different formulation and different raw materials, please do more testing before using it.