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Iindidi zeMveliso
iveliso ezifakiwe
01
I-HPMC yenqanaba leyeza
I-HPMC yenqanaba leyeza
I-HPMC yenqanaba leyeza
I-HPMC yenqanaba leyeza
I-HPMC yenqanaba leyeza
I-HPMC yenqanaba leyeza
I-HPMC yenqanaba leyeza
I-HPMC yenqanaba leyeza
I-HPMC yenqanaba leyeza
I-HPMC yenqanaba leyeza

I-HPMC yenqanaba leyeza

I-HPMC Hydroxypropyl methylcellulose yodidi lweyeza imhlophe okanye imhlophe njengobisi, ayinavumba, ayinancasa, ingumphunga okanye i-granule enemicu, ukwehla kobunzima xa yomiswa akudluli kwi-10%, iyanyibilika emanzini abandayo kodwa hayi emanzini ashushu, kancinci emanzini ashushu. Ukudumba, ukugabha, nokwenza isisombululo se-colloidal esiqinileyo, esiba sisisombululo xa sipholile, kwaye sibe yijeli xa sishushu.


I-Pharmaceutical Grade Hydroxypropyl Methylcellulose (HPMC) luhlobo olukhethekileyo lwe-HPMC olusetyenziswa kwishishini lamayeza. I-HPMC yipolymer enyibilikayo emanzini ephuma kwi-cellulose, kwaye xa isetyenziswa kwifomyula zamayeza, inika iingenelo ezininzi ezibalulekileyo kunye nokusetyenziswa.

    Qhagamshelana nathi
    iinkcukacha zemveliso

    Iinkcukacha zeKhemikhali

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    Inkcazo

    I-HPMC 60

    (2910)

    I-HPMC 65

    (2906)

    I-HPMC 75

    (2208)

    Ubushushu bejeli (℃)

    58-64

    62-68

    70-90

    I-Methoxy (WT%)

    28.0-30.0

    27.0-30.0

    19.0-24.0

    I-Hydroxypropoxy (WT%)

    7.0-12.0

    4.0-7.5

    4.0-12.0

    Ukuqina (i-cps, isisombululo se-2%)

    3, 5, 6, 15, 50, 100, 400, 4000, 10000, 40000, 60000, 100000, 150000, 200000

    Ibanga leMveliso:

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    Inkcazo

    I-HPMC 60

    (2910)

    I-HPMC 65

    (2906)

    I-HPMC 75

    (2208)

    Ubushushu bejeli (℃)

    58-64

    62-68

    70-90

    I-Methoxy (WT%)

    28.0-30.0

    27.0-30.0

    19.0-24.0

    I-Hydroxypropoxy (WT%)

    7.0-12.0

    4.0-7.5

    4.0-12.0

    Ukuqina (i-cps, isisombululo se-2%)

    3, 5, 6, 15, 50, 100, 400, 4000, 10000, 40000, 60000, 100000, 150000, 200000

    Isicelo

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    Isicelo se-Pharma Excipients

    Ibanga leMithi yeHPMC

    Idosi

    I-Laxative Eninzi

    75K4000,75K100000

    3-30%

    Iikhrimu, iiGel

    60E4000,75K4000

    1-5%

    Ukulungiselela Amehlo

    60E4000

    01.-0.5%

    Amalungiselelo e-Eye Drops

    60E4000

    0.1-0.5%

    Iarhente yokuMisa

    60E4000, 75K4000

    1-2%

    Iiantacids

    60E4000, 75K4000

    1-2%

    Isibopheleli seepilisi

    60E5, 60E15

    0.5-5%

    I-Convention Wet Granulation

    60E5, 60E15

    2-6%

    Iingubo zeTablet

    60E5, 60E15

    0.5-5%

    I-Matrix yoKhupho oluLawulwayo

    75K100000,75K15000

    20-55%

    iimveliso (1) ix8

    iimveliso (2)8ux

    Iimpawu eziphambili kunye nokusetyenziswa kwe-HPMC yoHlelo lweMithi:

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    1. Isibopheleli:

    I-HPMC isebenza njengesihlanganisi kwiifomyula zeepilisi zamayeza. Inceda ekubambeni izithako ezisebenzayo zamayeza (ii-API) kunye nezinto ezincedisayo ukuze zenze ithebhulethi edibeneyo enokuginywa lula.

    2. Ukungavumelani:

    Kwezinye iimeko, i-HPMC ingasetyenziswa njengesixhobo sokucoca iipilisi. Inceda ekuqhekekeni ngokukhawuleza kwepilisi ibe ngamasuntswana amancinci, okuvumela ukukhululwa nokufunxwa kwesiyobisi kwinkqubo yokugaya ukutya.

    3. Izinto zokugquma:

    I-HPMC isetyenziswa njengesixhobo sokufaka ifilimu kwiipilisi kunye neekhaphu, ikhusela iyeza, iphucula ukufihla incasa, kwaye ilawula ukukhutshwa kwe-API.

    4. Ukukhululwa Okuqhubekayo:

    Kwiifomyula ezikhutshwa ngokulawulwayo, i-HPMC ingasetyenziswa ukulawula ukukhululwa kwesiyobisi ngokuhamba kwexesha, inika isiphumo sonyango esihlala ixesha elide.

    5. Isiguquli seViscosity:

    Isebenza njengoguquli we-viscosity kwi-liquid kunye ne-semi-solid formulations, njenge-oral suspensions kunye ne-topical gels, ukulawula ukuhambelana kunye neempawu zokuhamba kwamanzi.

    6. Iarhente yeGelling:

    I-HPMC ingasetyenziswa njenge-arhente ye-gelling ekwenzeni ii-gel zomlomo kunye nee-mucilages ukuze kube lula ukuyisebenzisa.

    Ukusetyenziswa kwe-HPMC yeGrade yeMithi:

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    I-HPMC yePharmaceutical Grade isetyenziswa kakhulu kwiindlela ezahlukeneyo zokulinganisa amayeza, kuquka:

    1. Iipilisi:

    Yinto ebalulekileyo kwimixube yeepilisi, iqinisekisa ukubopha okufanelekileyo kwezithako kunye neempawu zokuqhekeka.

    2. Iikhaphu:

    I-HPMC ingasetyenziselwa iifomyula zekhaphu, zombini njenge-binder yokuzalisa umgubo kunye nenxalenye yeqokobhe lekhaphu ukuze ikhutshwe ixesha elide okanye ixesha elide.

    3. Iipilisi Ezigqunyiweyo:

    Iingubo zefilimu ezenziwe nge-HPMC zikhusela ithebhulethi kwaye zilawula ukukhutshwa kwesiyobisi.

    4. Izinto Ezixutywayo Ngomlomo:

    Kwiifomyula zolwelo, i-HPMC inokusebenza njengoguquli we-viscosity, izinzise ukumiswa.

    5. Iigels kunye neekrimu zeTopical:

    Isetyenziswa kwiifomyula ezisetyenziswa ngelaphu ukuze kufunyanwe ubume obufunekayo kunye nokuhambelana.

    6. Ii-Mucilages:

    I-HPMC ingasetyenziswa ekwenzeni ii-mucilages zokusetyenziswa ngomlomo.

    Iingenelo zokusebenzisa i-HPMC yoMgangatho weMithi:

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    - Ukubopha kunye nokuqhekeka kwethebhulethi okuphuculweyo.
    - Ukukhutshwa kwamayeza okulawulwayo ukuze kubekho iziphumo zonyango ezinde.
    - Ukufihla incasa kunye nokukhusela iyeza kwiipilisi ezigqunyiweyo.
    - Ukwakheka okuphuculweyo kunye nokungaguquguquki kwefomyula ezingamanzi kunye neziqinileyo.
    - Ifanelekile ukusetyenziswa kwiindlela ezahlukeneyo zokuthatha amayeza.

    I-HPMC yeCandelo leMithi idlala indima ebalulekileyo kushishino lwemithi, inegalelo kumgangatho kunye nokusebenza kweendlela ezahlukeneyo zamayeza. Iimpawu zayo zenza ukuba ibe yinto esebenziseka lula kwaye isetyenziswa kakhulu ekwenzeni iipilisi, iindlela ezilawulwayo zokukhupha amayeza, kunye nezinye iindlela zamayeza, ukuqinisekisa ukuba amayeza ayasebenza, azinzile, kwaye akhuselekile kwizigulana.

    Ukupakisha

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    Ukupakisha okuqhelekileyo yi-25kg/idrama yefayibha
    20'FCL: iitoni ezili-9 ezineepalethi; iitoni ezili-10 ezingafakwanga ipalethi.
    40'FCL: iitoni ezili-18 ezineepalethi; iitoni ezingama-20 ezingafakwanga ipalethi.

    Indawo yokugcina:

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    Yigcine kwindawo epholileyo, neyomileyo engaphantsi kwama-30°C kwaye ikhuselekile kumswakama kunye nokucinezelwa, kuba iimpahla zi-thermoplastic, ixesha lokugcina akufuneki lidlule iinyanga ezingama-36.

    Amanqaku okhuseleko:

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    Le datha ingentla ihambelana nolwazi lwethu, kodwa musa ukubakhulula abathengi ngononophelo xa beyijonga yonke ngononophelo kwangoko xa beyifumana. Ukuze uphephe ukwenziwa kwefomyula eyahlukileyo kunye nezinto ezahlukeneyo ezikrwada, nceda wenze uvavanyo oluthe kratya ngaphambi kokuba uyisebenzise.