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Izigaba Zemikhiqizo
Imikhiqizo Evelele
01
I-HPMC yezinga lemithi
I-HPMC yezinga lemithi
I-HPMC yezinga lemithi
I-HPMC yezinga lemithi
I-HPMC yezinga lemithi
I-HPMC yezinga lemithi
I-HPMC yezinga lemithi
I-HPMC yezinga lemithi
I-HPMC yezinga lemithi
I-HPMC yezinga lemithi

I-HPMC yezinga lemithi

I-HPMC Hydroxypropyl methylcellulose yezinga lemithi imhlophe noma imhlophe njengobisi, ayinaphunga, ayinambitheki, iyimpuphu noma i-granule enemicu, ukwehla kwesisindo lapho komiswa akudluli u-10%, kuyancibilika emanzini abandayo kodwa hhayi emanzini ashisayo, kancane kancane emanzini ashisayo. Ukuvuvukala, ukugaya, kanye nokwakha isixazululo se-colloidal esiqinile, esiba yisisombululo lapho sipholile, futhi sibe yijeli lapho sishiswa.


I-Pharmaceutical Grade Hydroxypropyl Methylcellulose (HPMC) iwuhlobo olukhethekile lwe-HPMC olusetshenziswa embonini yezemithi. I-HPMC iyi-polymer encibilika emanzini etholakala ku-cellulose, futhi uma isetshenziswa ekwakhiweni kwezemithi, inikeza izinzuzo eziningana ezibalulekile kanye nezicelo.

    Xhumana nathi
    imininingwane yomkhiqizo

    Ukucaciswa Kwamakhemikhali

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    Imininingwane

    I-HPMC 60

    (2910)

    I-HPMC 65

    (2906)

    I-HPMC 75

    (2208)

    Izinga lokushisa lejeli (℃)

    58-64

    62-68

    70-90

    I-Methoxy (WT%)

    28.0-30.0

    27.0-30.0

    19.0-24.0

    I-Hydroxypropoxy (WT%)

    7.0-12.0

    4.0-7.5

    4.0-12.0

    Ukuqina (i-cps, isixazululo esingu-2%)

    3, 5, 6, 15, 50, 100, 400,4000, 10000, 40000, 60000,100000,150000,200000

    Ibanga Lomkhiqizo:

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    Imininingwane

    I-HPMC 60

    (2910)

    I-HPMC 65

    (2906)

    I-HPMC 75

    (2208)

    Izinga lokushisa lejeli (℃)

    58-64

    62-68

    70-90

    I-Methoxy (WT%)

    28.0-30.0

    27.0-30.0

    19.0-24.0

    I-Hydroxypropoxy (WT%)

    7.0-12.0

    4.0-7.5

    4.0-12.0

    Ukuqina (i-cps, isixazululo esingu-2%)

    3, 5, 6, 15, 50, 100, 400,4000, 10000, 40000, 60000,100000,150000,200000

    Isicelo

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    Isicelo Sokusiza Ngemithi Yemithi

    Ibanga Lemithi i-HPMC

    Isilinganiso

    I-Bulk Laxative

    75K4000,75K100000

    3-30%

    Okhilimu, Amajeli

    60E4000,75K4000

    1-5%

    Ukulungiselela Amehlo

    60E4000

    01.-0.5%

    Amalungiselelo Amaconsi Eso

    60E4000

    0.1-0.5%

    I-ejenti Yokumisa

    60E4000, 75K4000

    1-2%

    Ama-antacid

    60E4000, 75K4000

    1-2%

    I-Tablet Binder

    60E5, 60E15

    0.5-5%

    I-Convention Wet Granulation

    60E5, 60E15

    2-6%

    Izembozo Zethebhulethi

    60E5, 60E15

    0.5-5%

    I-Matrix Yokukhishwa Elawulwayo

    75K100000,75K15000

    20-55%

    imikhiqizo (1) ix8

    imikhiqizo (2)8ux

    Izakhiwo Eziyinhloko Nokusetshenziswa Kwe-HPMC Yezinga Lemithi:

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    1. Isibopho:

    I-HPMC isebenza njengesihlanganisi ekwakhiweni kwamaphilisi emithi. Isiza ekubambeni izithako ezisebenzayo zemithi (ama-API) kanye nezinto ezisizayo ndawonye ukuze kwakheke iphilisi elihlangene elingagwinywa kalula.

    2. Ukungavumelani:

    Kwezinye izimo, i-HPMC ingasetshenziswa njenge-disintegrant kumaphilisi. Isiza ekuqhekekeni okusheshayo kwephilisi ibe yizinhlayiya ezincane, okuvumela ukukhululwa nokumuncwa komuthi ohlelweni lokugaya ukudla.

    3. Izinto Zokumboza:

    I-HPMC isetshenziswa njengento yokumboza ifilimu yamaphilisi nama-capsule, ihlinzeka ngokuvikelwa komuthi, ithuthukisa ukufihla ukunambitheka, futhi ilawula ukukhishwa kwe-API.

    4. Ukukhululwa Okuqhubekayo:

    Ezakhiweni zokukhululwa okulawulwayo, i-HPMC ingasetshenziswa ukulawula ukukhishwa komuthi ngokuhamba kwesikhathi, okuhlinzeka ngomphumela wezokwelapha oqhubekayo.

    5. Isiguquli se-Viscosity:

    Isebenza njengomuguquli we-viscosity ekwakhiweni okuwuketshezi kanye nokwe-semi-solid, njengokumiswa ngomlomo kanye nama-gel angaphandle, ukulawula ukuhambisana kanye nezakhiwo zokugeleza.

    6. I-ejenti ye-Gelling:

    I-HPMC ingasetshenziswa njenge-ejenti yokugaya ekwakhiweni kwamajeli omlomo kanye nama-mucilage ukuze kube lula ukuwasebenzisa.

    Ukusetshenziswa kwe-HPMC Yezinga Lemithi:

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    I-HPMC Yebanga Lemithi isetshenziswa kabanzi ezinhlotsheni ezahlukene zemithamo yemithi, okuhlanganisa:

    1. Amaphilisi:

    Kuyingxenye ebalulekile ekwakhiweni kwamaphilisi, okuqinisekisa ukubopha okufanele kwezithako kanye nezici zokuqhekeka.

    2. Amakapsuli:

    I-HPMC ingasetshenziswa ekwakhiweni kwama-capsule, kokubili njenge-binder yokugcwalisa i-powder kanye nanjengengxenye yegobolondo le-capsule yokukhululwa okubambezelekile noma okuqhubekayo.

    3. Amaphilisi Amboziwe:

    Izembozo zefilimu ezenziwe nge-HPMC zivikela ithebhulethi futhi zilawula ukukhishwa kwesidakamizwa.

    4. Ukumiswa Komlomo:

    Ezakhiweni zoketshezi, i-HPMC ingasebenza njengokushintsha i-viscosity, iqinise ukumiswa.

    5. Amajeli kanye nama-creams akhethekile:

    Isetshenziswa ekwakhiweni kwangaphandle ukuze kufezwe ukuthungwa nokuvumelana okufiselekayo.

    6. Ama-Mucilage:

    I-HPMC ingasetshenziswa ekwakhiweni kwezimpukane zokuphathwa ngomlomo.

    Izinzuzo Zokusebenzisa I-HPMC Yezinga Lemithi:

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    - Ukubopha nokuqhekeka kwethebhulethi okuthuthukisiwe.
    - Ukukhishwa kwemithi okulawulwayo kwemiphumela yokwelapha ende.
    - Ukufihla ukunambitha kanye nokuvikela umuthi kumaphilisi amboziwe.
    - Ukuthungwa okuthuthukisiwe kanye nokuvumelana okuthuthukisiwe kwezakhi zoketshezi kanye neziqinile kancane.
    - Kufaneleka ukusetshenziswa ezinhlotsheni ezahlukene zemithi.

    I-HPMC Yezinga Lemithi idlala indima ebalulekile embonini yezemithi, inikela ekhwalithini nasekusebenzeni kwezinhlobo ezahlukene zemithi. Izakhiwo zayo ziyenza ibe yisithako esisebenziseka kalula nesisetshenziswa kabanzi ekukhiqizeni amaphilisi, izinhlobo zokukhululwa okulawulwayo, kanye nezinye izinhlelo zokusebenza zemithi, okuqinisekisa ukuthi imithi iyasebenza, izinzile, futhi iphephile ezigulini.

    Ukupakisha

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    Ukupakisha okujwayelekile kungu-25kg/isigubhu se-Fibre
    20'FCL: Amathani ayi-9 ane-pallet; Amathani ayi-10 angafakwanga i-pallet.
    40'FCL: Amathani ayi-18 ane-pallet; Amathani angama-20 angafakwanga i-pallet.

    Isitoreji:

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    Yigcine endaweni epholile, eyomile engaphansi kuka-30°C futhi ivikelwe emswakama nasekucindezelweni, njengoba izimpahla zi-thermoplastic, isikhathi sokugcina akufanele sidlule izinyanga ezingu-36.

    Amanothi okuphepha:

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    Idatha engenhla ihambisana nolwazi lwethu, kodwa ungaxoleli amakhasimende ngokuyihlola ngokucophelela yonke ngokushesha lapho itholakala. Ukuze ugweme ukwakheka okuhlukile nezinto zokusetshenziswa ezahlukene, sicela wenze ukuhlolwa okwengeziwe ngaphambi kokuyisebenzisa.