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Lihlopha tsa Lihlahisoa
Lihlahisoa tse Hlahisitsoeng
01
HPMC ea sehlopha sa meriana
HPMC ea sehlopha sa meriana
HPMC ea sehlopha sa meriana
HPMC ea sehlopha sa meriana
HPMC ea sehlopha sa meriana
HPMC ea sehlopha sa meriana
HPMC ea sehlopha sa meriana
HPMC ea sehlopha sa meriana
HPMC ea sehlopha sa meriana
HPMC ea sehlopha sa meriana

HPMC ea sehlopha sa meriana

HPMC Hydroxypropyl methylcellulose ea sehlopha sa meriana e tšoeu kapa e tšoeu joaloka lebese, ha e na monko, ha e na tatso, e na le phofo kapa granule ea fibrous, ho theola boima ba 'mele ha ho omisoa ha ho fete 10%, e qhibiliha ka metsing a batang empa e se ka metsi a chesang, butle-butle ka metsing a chesang Ho ruruha, ho kenella ha metsi, le ho etsa tharollo ea colloidal e viscous, e fetohang tharollo ha e pholisitsoe, 'me e fetoha gel ha e futhumatsoa.


Hydroxypropyl Methylcellulose ea Sehlopha sa Meriana (HPMC) ke mofuta o ikhethileng oa HPMC o sebelisoang indastering ea meriana. HPMC ke polymer e qhibilihang ka metsing e nkiloeng ho cellulose, 'me ha e sebelisoa mefuteng ea meriana, e fana ka melemo le lits'ebetso tse' maloa tsa bohlokoa.

    Iteanye le rona
    lintlha tsa sehlahisoa

    Tlhaloso ea Lik'hemik'hale

    tlhaloso2

    Tlhaloso

    HPMC 60

    (2910)

    HPMC 65

    (2906)

    HPMC 75

    (2208)

    Mocheso oa gel (℃)

    58-64

    62-68

    70-90

    Methoxy (WT%)

    28.0-30.0

    27.0-30.0

    19.0-24.0

    Hydroxypropoxy (Boima ba 'mele%)

    7.0-12.0

    4.0-7.5

    4.0-12.0

    Ho thibana ha metsi (cps, 2% Tharollo)

    3, 5, 6, 15, 50, 100, 400, 4000, 10000, 40000, 60000, 100000, 150000, 200000

    Sehlopha sa Sehlahisoa:

    tlhaloso2

    Tlhaloso

    HPMC 60

    (2910)

    HPMC 65

    (2906)

    HPMC 75

    (2208)

    Mocheso oa gel (℃)

    58-64

    62-68

    70-90

    Methoxy (WT%)

    28.0-30.0

    27.0-30.0

    19.0-24.0

    Hydroxypropoxy (Boima ba 'mele%)

    7.0-12.0

    4.0-7.5

    4.0-12.0

    Ho thibana ha metsi (cps, 2% Tharollo)

    3, 5, 6, 15, 50, 100, 400, 4000, 10000, 40000, 60000, 100000, 150000, 200000

    Kopo

    tlhaloso2

    Kopo ea Lisebelisoa tsa Pharma

    HPMC ea Kereiti ea Meriana

    Tekanyo

    Setlolo sa ho ntsha lero ka bongata

    75K4000,75K100000

    3-30%

    Litlolo, Lijel

    60E4000,75K4000

    1-5%

    Tokisetso ea Mahlo

    60E4000

    01.-0.5%

    Litokisetso tsa Marotholi a Mahlo

    60E4000

    0.1-0.5%

    Moemeli ea Emisang

    60E4000, 75K4000

    1-2%

    Lithethefatsi tse loantšang asiti

    60E4000, 75K4000

    1-2%

    Matlapa a Binder

    60E5, 60E15

    0.5-5%

    Kopano ea Metsi Granulation

    60E5, 60E15

    2-6%

    Liaparo tsa Matlapa

    60E5, 60E15

    0.5-5%

    Matrix ea Tokollo e Laoloang

    75K100000,75K15000

    20-55%

    lihlahisoa (1) ix8

    lihlahisoa (2)8ux

    Matlotlo a Bohlokoa le Tšebeliso ea HPMC ea Sehlopha sa Meriana:

    tlhaloso2

    1. Setlama:

    HPMC e sebetsa e le sehokelo mefuteng ea matlapa a meriana. E thusa ho tšoara metsoako e sebetsang ea meriana (API) le metsoako e thusang ho etsa letlapa le kopaneng le ka mennoang habonolo.

    2. Ba sa amoheloeng:

    Maemong a mang, HPMC e ka sebelisoa e le sebolaya-dikokwana-hloko ka har'a matlapa. E thusa ho robeha ha letlapa ka potlako hore e be likaroloana tse nyane, e leng se lumellang ho lokolloa le ho monngoa ha moriana tsamaisong ea tšilo ea lijo.

    3. Lisebelisoa tsa ho roala:

    HPMC e sebelisoa e le thepa ea ho koahela filimi bakeng sa matlapa le li-capsule, e fana ka tšireletso bakeng sa moriana, e ntlafatsa ho koaheloa ha tatso, le ho laola ho lokolloa ha API.

    4. Tokollo e Tsitsitseng:

    Mefuteng e laoloang ea ho lokolloa, HPMC e ka sebelisoa ho fetola ho lokolloa ha moriana ha nako e ntse e ea, e leng se fanang ka phello ea phekolo e telele.

    5. Phetoho ea Viscosity:

    E sebetsa e le sesebelisoa sa ho fetola viscosity ka har'a metsoako e metsi le e tiileng hanyane, joalo ka li-suspension tse nooang le li-gel tse ka holim'a letlalo, ho laola botsitso le litšobotsi tsa phallo.

    6. Moemeli oa Gelling:

    HPMC e ka sebelisoa e le sesebelisoa sa ho etsa li-gelling ha ho etsoa li-gel tsa molomo le li-mucilage bakeng sa ho nolofatsa tsamaiso.

    Ditshebediso tsa HPMC ya Kereiti ya Meriana:

    tlhaloso2

    HPMC ea Sehlopha sa Meriana e sebelisoa haholo mefuteng e fapaneng ea tekanyo ea meriana, ho kenyeletsoa:

    1. Matlapa:

    Ke karolo ea bohlokoa mefuteng ea matlapa, e netefatsang ho tlamahana hantle ha metsoako le litšobotsi tsa ho qhibiliha.

    2. Dikhasete:

    HPMC e ka sebediswa bakeng sa diforomo tsa kapsule, e le sehokelo bakeng sa ho tlatsa phofo le e le karolo ya khetla ya kapsule bakeng sa ho dieha kapa ho ntsha tokollo e tswelang pele.

    3. Matlapa a koahetsoeng:

    Liaparo tsa filimi tse entsoeng ka HPMC li sireletsa letlapa le ho laola ho lokolloa ha moriana.

    4. Litšehetso tsa molomo:

    Mefuteng ea metsi, HPMC e ka sebetsa e le sesebelisoa sa ho fetola viscosity, e tsitsisa ho emisoa.

    5. Lijele le Litlolo tse Hloekisang:

    E sebelisoa mefuteng ea litlolo ho fihlela sebopeho le botsitso bo lakatsehang.

    6. Li-mucilage:

    HPMC e ka sebelisoa ho etsa li-mucilage bakeng sa ho nooa.

    Melemo ea ho Sebelisa HPMC ea Kereiti ea Meriana:

    tlhaloso2

    - Ho tlama le ho qhalana ha matlapa ho ntlafetse.
    - Tokollo e laoloang ea meriana bakeng sa litlamorao tse telele tsa kalafo.
    - Ho sireletsa tatso le ho sireletsa moriana matlapeng a koahetsoeng.
    - Sebopeho se ntlafetseng le botsitso ba metsoako e metsi le e tiileng hanyane.
    - E loketse ho sebelisoa ka mefuta e fapaneng ea tekanyo ea meriana.

    HPMC ea Sehlopha sa Meriana e bapala karolo ea bohlokoa indastering ea meriana, e tlatsetsa boleng le ts'ebetsong ea mefuta e fapaneng ea meriana. Thepa ea eona e etsa hore e be sesebelisoa se feto-fetohang le se sebelisoang haholo tlhahisong ea matlapa, mekhoa e laoloang ea ho lokolla, le lits'ebetsong tse ling tsa meriana, ho netefatsa hore meriana e sebetsa hantle, e tsitsitse ebile e bolokehile bakeng sa bakuli.

    Sephutheloana

    tlhaloso2

    Sepakete se tloaelehileng ke 25kg/moropa oa faeba
    20'FCL: lithane tse 9 tse nang le pallet e nang le liphalete; lithane tse 10 tse sa kenngoang pallet.
    40'FCL: lithane tse 18 tse nang le pallet e kentsoeng; lithane tse 20 tse sa kenngoang pallet.

    Polokelo:

    tlhaloso2

    E boloke sebakeng se pholileng, se omileng ka tlase ho 30°C 'me e sirelelitsoe khahlanong le mongobo le ho hatelloa, kaha thepa ke ea thermoplastic, nako ea polokelo ha ea lokela ho feta likhoeli tse 36.

    Lintlha tsa polokeho:

    tlhaloso2

    Lintlha tse ka holimo li lumellana le tsebo ea rona, empa u se ke ua lokolla bareki ba hlahlobang tsohle ka hloko hang ha li amoheloa. Ho qoba mokhoa o fapaneng oa ho kopanya le thepa e tala e fapaneng, ka kopo etsa liteko tse ling pele u e sebelisa.