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01
HPMC fasalka daawada
HPMC fasalka daawada
HPMC fasalka daawada
HPMC fasalka daawada
HPMC fasalka daawada
HPMC fasalka daawada
HPMC fasalka daawada
HPMC fasalka daawada
HPMC fasalka daawada
HPMC fasalka daawada

HPMC fasalka daawada

Nooca daawada HPMC Hydroxypropyl methylcellulose waa cad ama caano cad, ur la'aan, dhadhan la'aan, budo fiiber leh ama granule, miisaanka oo yaraada marka la qalajiyo kama badna 10%, wuxuu ku milmaa biyo qabow laakiin ma aha biyo kulul, si tartiib tartiib ah ayuu ugu milmaa biyaha kulul. Barar, peptization, iyo sameynta xal colloidal ah oo fiiqan, kaas oo noqda xal marka la qaboojiyo, wuxuuna noqdaa jel marka la kululeeyo.


Daawada Heerka Hydroxypropyl Methylcellulose (HPMC) waa nooc gaar ah oo ka mid ah HPMC oo loo isticmaalo warshadaha dawooyinka. HPMC waa polymer-ka biyaha ku milma oo laga soo saaro cellulose, marka lagu dabaqo qaacidooyinka dawooyinka, waxay bixisaa faa'iidooyin iyo codsiyo dhowr ah oo muhiim ah.

    Nala soo xiriir
    faahfaahinta alaabta

    Qeexitaanka Kiimikada

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    Faahfaahinta

    HPMC 60

    (2910)

    HPMC 65

    (2906)

    HPMC 75

    (2208)

    Heerkulka jel (℃)

    58-64

    62-68

    70-90

    Methoxy (WT%)

    28.0-30.0

    27.0-30.0

    19.0-24.0

    Hydroxypropoxy (WT%)

    7.0-12.0

    4.0-7.5

    4.0-12.0

    Viscosity (cps, 2% Xal)

    3, 5, 6, 15, 50, 100, 400, 400, 40000, 10000, 40000, 60000, 100000, 150000, 200000

    Heerka Badeecada:

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    Faahfaahinta

    HPMC 60

    (2910)

    HPMC 65

    (2906)

    HPMC 75

    (2208)

    Heerkulka jel (℃)

    58-64

    62-68

    70-90

    Methoxy (WT%)

    28.0-30.0

    27.0-30.0

    19.0-24.0

    Hydroxypropoxy (WT%)

    7.0-12.0

    4.0-7.5

    4.0-12.0

    Viscosity (cps, 2% Xal)

    3, 5, 6, 15, 50, 100, 400, 400, 40000, 10000, 40000, 60000, 100000, 150000, 200000

    Codsiga

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    Codsiga Waxyaabaha Daawada ah ee Farmashiyaha

    Fasalka Daawada HPMC

    Qiyaasta

    Jilciye Badan

    75K4000,75K100000

    3-30%

    Kareemyada, Jel

    60E4000,75K4000

    1-5%

    Diyaarinta Indhaha

    60E4000

    01.-0.5%

    Diyaarinta Dhibcaha Indhaha

    60E4000

    0.1-0.5%

    Wakiilka Joojinta

    60E4000, 75K4000

    1-2%

    Daawooyinka lidka asiidhka

    60E4000, 75K4000

    1-2%

    Kiniiniyada Galka

    60E5, 60E15

    0.5-5%

    Qoyanta Qoyan ee Shirka

    60E5, 60E15

    2-6%

    Dahaarka Kiniiniga

    60E5, 60E15

    0.5-5%

    Matrix-ka Sii-deynta La Xakameeyay

    75K100000,75K15000

    20-55%

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    Sifooyinka Muhiimka ah iyo Isticmaalka HPMC-ga Darajada Daawada:

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    1. Xidhmo:

    HPMC waxay u dhaqantaa sidii qalab isku xidha daawooyinka kiniiniyada. Waxay ka caawisaa inay isku xidho maaddooyinka daawada firfircoon (APIs) iyo walxaha ka qayb qaata si ay u sameeyaan kiniin isku dhafan oo si fudud loo liqi karo.

    2. Kala-goys:

    Xaaladaha qaarkood, HPMC waxaa loo isticmaali karaa sidii walax lagu kala diro kiniiniyada. Waxay ka caawisaa in si degdeg ah kiniinka loogu kala jaro qaybo yaryar, taasoo u oggolaanaysa sii deynta iyo nuugista daawada nidaamka dheefshiidka.

    3. Qalabka Dahaadhka:

    HPMC waxaa loo isticmaalaa sidii agab dahaadh filim ah oo loogu talagalay kiniiniyada iyo kaabsulka, iyadoo la siinayo ilaalin daawada, la hagaajinayo maaskarada dhadhanka, iyo la xakameeyo sii deynta API-ga.

    4. Sii-deyn Waarta:

    Qaababka sii-deynta la xakameeyey, HPMC waxaa loo isticmaali karaa in lagu beddelo sii-deynta daawada waqti ka dib, taasoo bixinaysa saameyn daaweyn oo dheer.

    5. Wax ka Beddelaha Viscosity-ga:

    Waxay u adeegtaa sidii wax ka beddele viscosity ah oo ku jira qaacidooyinka dareeraha ah iyo kuwa nus-adag, sida joojinta afka iyo jelka maqaarka la mariyo, si loo xakameeyo isku-dheellitirka iyo sifooyinka socodka.

    6. Wakiilka Jelling-ka:

    HPMC waxaa loo isticmaali karaa sidii wakiilka jelitaanka marka la samaynayo jel afka laga qaato iyo mucilages si loo fududeeyo maamulka.

    Codsiyada HPMC Fasalka Daawada:

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    Fasalka Daawada HPMC waxaa si weyn loogu isticmaalaa qaabab daawo oo kala duwan, oo ay ku jiraan:

    1. Kiniiniyada:

    Waa qayb muhiim ah oo ka mid ah qaacidooyinka kiniiniga, iyadoo hubinaysa isku xidhka saxda ah ee maaddooyinka iyo astaamaha kala-goynta.

    2. Kaabsul:

    HPMC waxaa loo isticmaali karaa qaacidooyinka kaabsal, labadaba sidii xidhe loogu talagalay buuxinta budada iyo qayb ka mid ah qolofka kaabsal si loo sii daayo dib u dhac ama joogto ah.

    3. Kiniiniyada Dahaarka leh:

    Dahaarka filimka ee laga sameeyay HPMC ayaa ilaaliya kiniinka waxayna xakameeyaan sii deynta daawada.

    4. Joojinta Afka ah:

    Qaababka dareeraha ah, HPMC waxay u dhaqmi kartaa sidii wax ka beddele viscosity ah, taasoo dejinaysa joojinta.

    5. Jel iyo kareemo la mariyo:

    Waxaa loo isticmaalaa qaab-dhismeedka maqaarka si loo gaaro qaab-dhismeedka iyo isku-dhafka la rabo.

    6. Mucilages:

    HPMC waxaa loo isticmaali karaa qaabaynta mucilages-ka loogu talagalay maamulka afka.

    Faa'iidooyinka Isticmaalka HPMC Fasalka Daawada:

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    - Isku xidhka kiniinka iyo kala-goynta oo la hagaajiyay.
    - Sii daynta la xakameeyey ee daawooyinka si loo helo saameyn daaweyn oo dheer.
    - Dhadhanka maaskarada iyo ilaalinta daawada kiniiniyada dahaarka leh.
    - Qaab-dhismeed iyo isku-dheellitirnaan la xoojiyay oo ku jira qaacidooyinka dareeraha ah iyo kuwa nus-adag.
    - Ku habboon in loo isticmaalo noocyada kala duwan ee daawada qiyaasta.

    Darajada Daawada HPMC waxay door muhiim ah ka ciyaartaa warshadaha dawooyinka, iyadoo gacan ka geysaneysa tayada iyo waxqabadka daawooyinka kala duwan. Sifooyinkeedu waxay ka dhigayaan mid waxtar badan leh oo si ballaaran loo isticmaalo soo saarista kiniiniyada, qaacidooyinka la xakameeyey ee sii daynta, iyo codsiyada kale ee dawooyinka, iyadoo hubineysa in daawooyinku ay yihiin kuwo wax ku ool ah, deggan, oo ammaan u ah bukaanada.

    Baakad

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    Baakaynta caadiga ah waa 25kg/durbaanka Fiber
    20'FCL: 9 tan oo leh balaastiig; 10 tan oo aan balaastiig lahayn.
    40'FCL: 18 tan oo leh balaastiig; 20 tan oo aan balaastiig lahayn.

    Kaydinta:

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    Ku kaydi meel qabow oo qalalan oo ka hooseysa 30°C oo ka ilaali qoyaanka iyo cadaadiska, maadaama alaabtu ay tahay mid thermoplastic ah, waqtiga kaydinta waa inaanu ka badnayn 36 bilood.

    Qoraallada badbaadada:

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    Xogta kor ku xusan waxay waafaqsan tahay aqoontayada, laakiin ha ka cafin macaamiisha si taxaddar leh u hubinta dhammaantood isla markiiba marka la helo. Si looga fogaado qaacidooyinka kala duwan iyo walxaha ceeriin ee kala duwan, fadlan samee baaritaan dheeraad ah ka hor intaadan isticmaalin.