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Magulu a Zamalonda
Zogulitsa Zodziwika
01
Mankhwala a HPMC
Mankhwala a HPMC
Mankhwala a HPMC
Mankhwala a HPMC
Mankhwala a HPMC
Mankhwala a HPMC
Mankhwala a HPMC
Mankhwala a HPMC
Mankhwala a HPMC
Mankhwala a HPMC

Mankhwala a HPMC

Mankhwala a HPMC Hydroxypropyl methylcellulose ndi oyera kapena a mkaka, opanda fungo, opanda kukoma, ufa kapena granule wa ulusi, kuchepetsa thupi mukauma sikupitirira 10%, kumasungunuka m'madzi ozizira koma osati m'madzi otentha, pang'onopang'ono m'madzi otentha. Kutupa, kutsekeka, ndikupanga yankho la colloidal lokhuthala, lomwe limakhala yankho likazizira, ndipo limakhala gel likatenthedwa.


Mankhwala Opangira Mankhwala Hydroxypropyl Methylcellulose (HPMC) ndi mtundu wapadera wa HPMC womwe umagwiritsidwa ntchito mumakampani opanga mankhwala. HPMC ndi polima wosungunuka m'madzi wochokera ku cellulose, ndipo ikagwiritsidwa ntchito popanga mankhwala, imapereka maubwino ndi ntchito zingapo zofunika.

    Lumikizanani nafe
    tsatanetsatane wa malonda

    Kufotokozera kwa Mankhwala

    kufotokozera2

    Kufotokozera

    HPMC 60

    (2910)

    HPMC 65

    (2906)

    HPMC 75

    (2208)

    Kutentha kwa gel (℃)

    58-64

    62-68

    70-90

    Methoxy (WT%)

    28.0-30.0

    27.0-30.0

    19.0-24.0

    Hydroxypropoxy (WT%)

    7.0-12.0

    4.0-7.5

    4.0-12.0

    Kukhuthala (cps, 2% Yankho)

    3, 5, 6, 15, 50, 100, 400, 4000, 10000, 40000, 60000, 100000, 150000, 200000

    Kalasi ya Zamalonda:

    kufotokozera2

    Kufotokozera

    HPMC 60

    (2910)

    HPMC 65

    (2906)

    HPMC 75

    (2208)

    Kutentha kwa gel (℃)

    58-64

    62-68

    70-90

    Methoxy (WT%)

    28.0-30.0

    27.0-30.0

    19.0-24.0

    Hydroxypropoxy (WT%)

    7.0-12.0

    4.0-7.5

    4.0-12.0

    Kukhuthala (cps, 2% Yankho)

    3, 5, 6, 15, 50, 100, 400, 4000, 10000, 40000, 60000, 100000, 150000, 200000

    Kugwiritsa ntchito

    kufotokozera2

    Kugwiritsa Ntchito Mankhwala Owonjezera Mankhwala

    Mankhwala a HPMC

    Mlingo

    Mankhwala Otulutsa Thupi Ambiri

    75K4000,75K100000

    3-30%

    Ma kirimu, Ma Gel

    60E4000,75K4000

    1-5%

    Kukonzekera kwa Maso

    60E4000

    01.-0.5%

    Kukonzekera kwa Madontho a M'maso

    60E4000

    0.1-0.5%

    Wothandizira Kuyimitsa

    60E4000, 75K4000

    1-2%

    Mankhwala oletsa asidi

    60E4000, 75K4000

    1-2%

    Mapiritsi Opangira Mapiritsi

    60E5, 60E15

    0.5-5%

    Msonkhano Wonyowa Granulation

    60E5, 60E15

    2-6%

    Zophimba Mapiritsi

    60E5, 60E15

    0.5-5%

    Matrix Yotulutsidwa Yolamulidwa

    75K100000,75K15000

    20-55%

    zinthu (1) ix8

    zinthu (2)8ux

    Katundu Wofunika Kwambiri ndi Ntchito za HPMC Yopangira Mankhwala:

    kufotokozera2

    1. Chomangira:

    HPMC imagwira ntchito ngati chomangira mu mapiritsi opangira mankhwala. Imathandiza kulumikiza zosakaniza zogwira ntchito zamankhwala (APIs) ndi zosakaniza pamodzi kuti apange piritsi logwirizana lomwe lingathe kumezedwa mosavuta.

    2. Osasinthika:

    Nthawi zina, HPMC ingagwiritsidwe ntchito ngati mankhwala ophera tizilombo toyambitsa matenda. Imathandiza kuti piritsi ligawike mwachangu kukhala tinthu tating'onoting'ono, zomwe zimathandiza kuti mankhwala atuluke ndi kuyamwa m'mimba.

    3. Zopangira Zophimba:

    HPMC imagwiritsidwa ntchito ngati chinthu chophikira filimu ya mapiritsi ndi makapisozi, kupereka chitetezo cha mankhwalawa, kukonza kukoma, komanso kuwongolera kutulutsidwa kwa API.

    4. Kumasulidwa Kosatha:

    Mu mankhwala opangidwa ndi mankhwala oletsa kutulutsidwa, HPMC ingagwiritsidwe ntchito kusintha kutulutsidwa kwa mankhwala pakapita nthawi, zomwe zimapangitsa kuti chithandizo chikhale chothandiza kwa nthawi yayitali.

    5. Chosinthira Kukhuthala:

    Imagwira ntchito ngati chosinthira kukhuthala kwa viscosity mu mapangidwe amadzimadzi ndi theka-solid, monga zoyimitsidwa pakamwa ndi ma gels apakhungu, kuti ilamulire kusinthasintha ndi kayendedwe kake.

    6. Wothandizira Kupaka Gelling:

    HPMC ingagwiritsidwe ntchito ngati mankhwala opangira jeli pakamwa ndi mucilage kuti iperekedwe mosavuta.

    Kugwiritsa ntchito mankhwala a HPMC:

    kufotokozera2

    Mankhwala a HPMC amagwiritsidwa ntchito kwambiri m'njira zosiyanasiyana zoyezera mankhwala, kuphatikizapo:

    1. Mapiritsi:

    Ndi gawo lofunika kwambiri pakupanga mapiritsi, kuonetsetsa kuti zosakanizazo zimamangiriridwa bwino komanso kuti zinthuzo zigawike.

    2. Makapisozi:

    HPMC ingagwiritsidwe ntchito popanga ma capsule, monga chomangira ufa komanso ngati gawo la chipolopolo cha capsule kuti chitulutsidwe mochedwa kapena mosalekeza.

    3. Mapiritsi Ophimbidwa:

    Zophimba zopangidwa ndi filimu zopangidwa ndi HPMC zimateteza piritsi ndikulamulira kutuluka kwa mankhwalawa.

    4. Mankhwala Oletsa Kumwa:

    Mu mankhwala amadzimadzi, HPMC imatha kugwira ntchito ngati chosinthira kukhuthala, ndikukhazikitsa kuyimitsidwa.

    5. Ma Gel ndi Ma Cream Opaka Pakhungu:

    Amagwiritsidwa ntchito popanga zinthu zopaka pamwamba kuti akwaniritse kapangidwe ndi kusinthasintha komwe amafunikira.

    6. Mabala a mucilage:

    HPMC ingagwiritsidwe ntchito popanga ma mucilages kuti iperekedwe pakamwa.

    Ubwino Wogwiritsa Ntchito Mankhwala Opangira HPMC:

    kufotokozera2

    - Kumangirira bwino mapiritsi ndi kusweka kwawo.
    - Kutulutsa mankhwala kolamulidwa kuti kuthandize kuchiza nthawi yayitali.
    - Kuphimba kukoma ndi kuteteza mankhwala m'mapiritsi okhala ndi zokutira.
    - Kulimbitsa kapangidwe kake ndi kusinthasintha kwa kapangidwe ka madzi ndi kolimba pang'ono.
    - Yoyenera kugwiritsidwa ntchito m'njira zosiyanasiyana zoyezera mankhwala.

    Mankhwala a HPMC a gulu la mankhwala amagwira ntchito yofunika kwambiri mumakampani opanga mankhwala, zomwe zimathandiza kuti mitundu yosiyanasiyana ya mankhwala ikhale yabwino komanso igwire bwino ntchito. Kapangidwe kake kamapangitsa kuti ikhale yothandiza kwambiri popanga mapiritsi, mankhwala opangidwa molamulidwa, komanso ntchito zina zamankhwala, kuonetsetsa kuti mankhwala ndi othandiza, okhazikika, komanso otetezeka kwa odwala.

    Kulongedza

    kufotokozera2

    Kulongedza kokhazikika ndi 25kg/Ulusi ng'oma
    20'FCL: matani 9 okhala ndi mapaleti; matani 10 osapakidwa mapaleti.
    40'FCL: matani 18 okhala ndi mapaleti; matani 20 osapakidwa mapaleti.

    Malo Osungira:

    kufotokozera2

    Sungani pamalo ozizira, ouma osapitirira 30°C ndipo mutetezedwe ku chinyezi ndi kukanikiza, popeza katunduyo ndi thermoplastic, nthawi yosungira siyenera kupitirira miyezi 36.

    Zolemba zachitetezo:

    kufotokozera2

    Deta yomwe ili pamwambapa ikugwirizana ndi zomwe tikudziwa, koma musalole makasitomala kuti aziyang'ana zonse mosamala nthawi yomweyo akalandira. Kuti mupewe mitundu yosiyanasiyana ya mankhwala ndi zinthu zosiyanasiyana zopangira, chonde yesani zambiri musanagwiritse ntchito.