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Ngwaahịa Nkewa
Ngwaahịa Ndị A Mapụtara
01
Ọkwa ọgwụ HPMC
Ọkwa ọgwụ HPMC
Ọkwa ọgwụ HPMC
Ọkwa ọgwụ HPMC
Ọkwa ọgwụ HPMC
Ọkwa ọgwụ HPMC
Ọkwa ọgwụ HPMC
Ọkwa ọgwụ HPMC
Ọkwa ọgwụ HPMC
Ọkwa ọgwụ HPMC

Ọkwa ọgwụ HPMC

Ọgwụ HPMC Hydroxypropyl methylcellulose bụ ọcha ma ọ bụ mmiri ara ehi ọcha, enweghị isi, enweghị uto, ntụ ntụ fibrous ma ọ bụ granule, mbelata ibu mgbe a kpọrọ nkụ anaghị agafe 10%, ọ na-agbaze na mmiri oyi mana ọ bụghị mmiri ọkụ, nwayọ nwayọ na mmiri ọkụ Ọzịza, peptization, na ịmepụta mmiri colloidal viscous, nke na-aghọ ihe ngwọta mgbe a jụrụ oyi, ma na-aghọ gel mgbe a na-ekpo ọkụ.


Ọgwụ Phartial Grade Hydroxypropyl Methylcellulose (HPMC) bụ ụdị HPMC pụrụ iche nke eji eme ihe n'ụlọ ọrụ ọgwụ. HPMC bụ polima mmiri na-agbaze nke sitere na cellulose, ma mgbe etinyere ya na ọgwụ, ọ na-enye ọtụtụ uru na ngwa dị mkpa.

    Kpọtụrụ anyị
    nkọwa ngwaahịa

    Nkọwapụta Kemịkalụ

    nkọwa2

    Nkọwapụta

    HPMC 60

    (2910)

    HPMC 65

    (2906)

    HPMC 75

    (2208)

    Okpomọkụ jel (℃)

    58-64

    62-68

    70-90

    Usoro (WT%)

    28.0-30.0

    27.0-30.0

    19.0-24.0

    Hydroxypropoxy (WT%)

    7.0-12.0

    4.0-7.5

    4.0-12.0

    Viscosity (cps, 2% Ngwọta)

    3, 5, 6, 15, 50, 100, 400, 400, 10000, 40000, 60000, 100000, 150000, 200000

    Ọkwa Ngwaahịa:

    nkọwa2

    Nkọwapụta

    HPMC 60

    (2910)

    HPMC 65

    (2906)

    HPMC 75

    (2208)

    Okpomọkụ jel (℃)

    58-64

    62-68

    70-90

    Usoro (WT%)

    28.0-30.0

    27.0-30.0

    19.0-24.0

    Hydroxypropoxy (WT%)

    7.0-12.0

    4.0-7.5

    4.0-12.0

    Viscosity (cps, 2% Ngwọta)

    3, 5, 6, 15, 50, 100, 400, 400, 10000, 40000, 60000, 100000, 150000, 200000

    Ngwa

    nkọwa2

    Ngwa Ihe Ndị Na-enweta Ọgwụ

    Ọgwụ ọkwa HPMC

    Ọnụọgụ ọgwụ

    Nnukwu ihe mkpofu

    75K4000,75K100000

    3-30%

    Ude, gels

    60E4000,75K4000

    1-5%

    Nkwadebe Anya

    60E4000

    01.-0.5%

    Nkwadebe maka Ntụpụ Anya

    60E4000

    0.1-0.5%

    Onye Nkwụsị

    60E4000, 75K4000

    1-2%

    Ọgwụ mgbochi asịd

    60E4000, 75K4000

    1-2%

    Mbadamba ihe njide

    60E5, 60E15

    0.5-5%

    Mgbakọ Mmiri Mmiri

    60E5, 60E15

    2-6%

    Mkpuchi Mbadamba

    60E5, 60E15

    0.5-5%

    Matrix Mwepụta A Na-achịkwa

    75K100000,75K15000

    20-55%

    ngwaahịa (1)ix8

    ngwaahịa (2)8ux

    Isi ihe na ojiji nke ọkwa ọgwụ HPMC:

    nkọwa2

    1. Ihe njide:

    HPMC na-arụ ọrụ dị ka ihe na-ejikọ ọgwụ na ọgwụ. Ọ na-enyere aka ijikọ ihe ndị na-arụ ọrụ na ọgwụ (APIs) na ihe ndị na-enyere aka mee ka mbadamba ahụ dị n'otu nke enwere ike iri ngwa ngwa.

    2. Ihe na-emebi ihe:

    N'ọnọdụ ụfọdụ, enwere ike iji HPMC mee ihe dị ka ihe na-emebi ihe na mbadamba. Ọ na-enyere aka na mmebi ngwa ngwa nke mbadamba ahụ ka ọ bụrụ obere ihe, na-enye ohere ka a tọhapụ ma nabata ọgwụ ahụ na sistemu nri.

    3. Ihe mkpuchi:

    A na-eji HPMC eme ihe dị ka ihe mkpuchi ihe nkiri maka mbadamba na kapsụl, na-enye nchebe maka ọgwụ ahụ, na-eme ka ihe mkpuchi ahụ dịkwuo mma, ma na-achịkwa mwepụta nke API ahụ.

    4. Ntọhapụ Na-adịgide Adịgide:

    N'ime usoro mwepụta a na-achịkwa, enwere ike iji HPMC mee ihe iji gbanwee mwepụta ọgwụ ahụ ka oge na-aga, na-enye mmetụta ọgwụgwọ ogologo oge.

    5. Ihe Na-agbanwe Viscosity:

    Ọ na-arụ ọrụ dị ka ihe na-agbanwe viscosity n'ime usoro mmiri mmiri na nke ọkara siri ike, dị ka nkwusioru ọnụ na gels dị n'elu, iji chịkwaa nguzozi na njirimara mmiri.

    6. Ihe na-eme ka ihe na-egbu egbu:

    Enwere ike iji HPMC mee ihe dị ka ihe na-eme ka a na-ete mmanụ n'ọnụ na ihe ndị na-eme ka ọ dị mfe iji.

    Ngwa nke Pharmaceutical ọkwa HPMC:

    nkọwa2

    A na-eji HPMC Pharmaceutical Grade eme ihe n'ọtụtụ ụdị ọgwụ dị iche iche, gụnyere:

    1. Mbadamba:

    Ọ bụ ihe dị mkpa na ọgwụ mbadamba, na-ahụ na ejiri ihe ndị e ji mee ya na njirimara nke ịgbasa ya jikọtara nke ọma.

    2. Mkpụrụọgwụ:

    Enwere ike iji HPMC mee ihe maka ọgwụ capsules, ma dị ka ihe na-ejikọ ihe maka ntụ ntụ ahụ ma dị ka akụkụ nke shei capsule maka mwepụta oge ma ọ bụ na-adịgide adịgide.

    3. Mbadamba ndị a kpuchiri ekpuchi:

    Ihe mkpuchi ihe nkiri e ji HPMC mee na-echebe mbadamba ahụ ma na-achịkwa mwepụta ọgwụ ahụ.

    4. Nkwụsịtụ ọnụ:

    N'ime usoro mmiri mmiri, HPMC nwere ike ịrụ ọrụ dị ka ihe na-agbanwe viscosity, na-eme ka nkwụsịtụ ahụ sie ike.

    5. Gel na ude ndị a na-eji n'elu ihe:

    A na-eji ya eme ihe n'elu ihe ndị e ji eme ihe iji nweta udidi na ịdị n'otu achọrọ.

    6. Ihe eji egwu egwu:

    Enwere ike iji HPMC mee ihe n'ịhazi ihe ndị e ji amị mkpụrụ maka ịṅụ ya n'ọnụ.

    Uru nke Iji Ọgwụ Klas HPMC:

    nkọwa2

    - Mgbakwunye na mmebi nke mbadamba ka mma.
    - Mwepụta ọgwụ a na-achịkwa maka mmetụta ọgwụgwọ ogologo oge.
    - Ịmepụta ihe mkpuchi na ichebe ọgwụ ahụ n'ime mbadamba mkpuchi.
    - Ọdịdị na nguzozi dị mma n'ime usoro mmiri mmiri na nke ọkara siri ike.
    - Dabara adaba maka ojiji n'ụdị ọgwụ dị iche iche.

    Ọgwụ HPMC na-arụ ọrụ dị oke mkpa n'ụlọ ọrụ ọgwụ, na-enye aka n'ịdị mma na arụmọrụ nke ụdị ọgwụ dị iche iche. Ihe ndị dị na ya na-eme ka ọ bụrụ ihe na-enye aka nke ukwuu ma na-ejikarị eme ihe n'ichepụta mbadamba, usoro a na-achịkwa-ewepụta, na ngwa ọgwụ ndị ọzọ, na-eme ka ọgwụ ndị ahụ dị irè, kwụsie ike, ma dịkwa mma maka ndị ọrịa.

    Nkwakọ ngwaahịa

    nkọwa2

    Nkwakọ ngwaahịa ọkọlọtọ bụ 25kg/Fiber drum
    20'FCL: tọn 9 nwere palletized; tọn 10 enweghị palletized.
    40'FCL: tọn 18 nwere palletized; tọn 20 enweghị palletized.

    Nchekwa:

    nkọwa2

    Debe ya n'ebe dị jụụ ma kpọọ nkụ n'okpuru 30°C ma chebe ya pụọ ​​na iru mmiri na ịpị, ebe ọ bụ na ngwaahịa ahụ bụ thermoplastic, oge nchekwa ekwesịghị ịgafe ọnwa 36.

    Ihe ndetu nchekwa:

    nkọwa2

    Ihe ndị a dị n'elu kwekọrọ na ihe anyị maara, mana ewepụla ndị ahịa gị nke ọma ka ha lelee ha ozugbo ha natara ha. Iji zere ụdị usoro dị iche iche na ihe ndị dị iche iche, biko mee nnwale ndị ọzọ tupu i jiri ha.