Mokhoa oa ho Lokisa Li-Ether tse Hloekileng tsa Cellulose tsa HPMC
Hydroxypropyl Methylcellulose (HPMC) ke ether ea cellulose e feto-fetohang e sebelisoang liindastering tse fapaneng, ho kenyeletsoa kaho, meriana le lijo. Tataiso ena e fana ka kakaretso e felletseng ea ts'ebetso ea ho lokisa li-ether tsa cellulose tsa HPMC tse hloekileng, e totobatsa mehato le mekhoa ea bohlokoa e amehang.
Lisebelisoa tse tala le Tokisetso ea Pele
- Khetho ea Cellulose e tala
Tlhaloso: Tokisetso ea HPMC e qala ka cellulose ea boleng bo holimo, eo hangata e nkiloeng k'hothoneng kapa lehong. Bohloeki ba cellulose bo bohlokoa bakeng sa ho hlahisa HPMC ea boleng bo holimo.
Mehato:
- Khetha mehloli ea cellulose e hloekileng haholo.
- Etsa tlhoekiso ea pele ho tlosa litšila.
- Alkalization
Tlhaloso: Cellulose e phekoloa ka tharollo ea alkali, hangata sodium hydroxide (NaOH), ho etsa alkali cellulose. Mohato ona o kenya tšebetsong cellulose bakeng sa etherification.
Mehato:
- Koahela cellulose ka har'a tharollo ea NaOH.
- Lumella karabelo ho tsoela pele mochesong o laoloang le ka nako e behiloeng.
- Tobetsa tharollo e feteletseng ea alkali.
Ts'ebetso ea Etherification
- Karabelo ea Etherification
Tlhaloso: Alkali cellulose e feta ho etherification ka methyl chloride (CH3Cl) le propylene oxide (C3H6O) ho theha HPMC. Tekanyo ea phetolo (DS) le phetolo ea molar (MS) li khetholla litšobotsi tsa sehlahisoa sa ho qetela.
Mehato:
- Kenya methyl chloride le propylene oxide tlas'a maemo a laoloang.
- Boloka karabelo ka har'a reactor e koetsoeng ho laola khatello le mocheso.
- Netefatsa kabo e ts'oanang ea li-reagent bakeng sa boleng bo tsitsitseng ba sehlahisoa.
- Ho se nke lehlakore le ho hlatswa
Tlhaloso: Kamora ho etherification, motsoako oa karabelo oa koaheloa ebe oa hlatsuoa ho tlosa lik'hemik'hale tse setseng le lihlahisoa tse ling.
Mehato:
- Fokotsa motsoako oa karabelo ka ho sebelisa asiti, eo hangata e leng asetiki.
- Hlatsoa HPMC ka makhetlo a mangata ka metsi ho tlosa litšila le masalla a metsoako.
Ho Hloekisa le ho Omisa
- Tlhoekiso
Tlhaloso: Ho hlwekisa ho kenyelletsa ho hlatswa le ho sefa ho eketsehileng ho netefatsa hore ho tloswa ditshila dife kapa dife tse setseng, ho fihlella bohloeki bo phahameng ba HPMC.
Mehato:
- Sebelisa mekhoa ea ho sefa ho arola HPMC ho karolo ea mokelikeli.
- Hlatsoa HPMC ka ethanol kapa metsoako e meng e loketseng ho ntlafatsa bohloeki.
- Ho omisa
Tlhaloso: HPMC e hloekisitsoeng e omisitsoe ho tlosa mongobo, e leng ntho ea bohlokoa bakeng sa botsitso ba polokelo le ts'ebeliso e bonolo.
Mehato:
- Sebelisa mekhoa ea ho omisa ka vacuum kapa ea ho fafatsa ka spray.
- Netefatsa maemo a ho omisa a laolehileng ho thibela ho senyeha ha sehlahisoa.
Ts'ebetso ea ho Qetela
- Ho Sila le ho Sila
Tlhaloso: HPMC e omisitsweng e silwa ho ba phofo e ntle mme e sefshoa ho fihlella kabo e lakatsehang ya boholo ba dikarolwana.
Mehato:
- Sila HPMC e omisitsoeng u sebelisa li-mill tse loketseng.
- Sefa phofo ho fumana boholo bo lekanang ba dikarolwana.
- Taolo ea Boleng
TlhalosoLiteko tsa taolo ea boleng lia etsoa ho netefatsa hore HPMC e fihlela litlhoko tse hlokahalang bakeng sa bohloeki, ho teteana, le liparamente tse ling.
Mehato:
- Etsa liteko tsa ho teteana, mongobo, tekanyo ea ho nkeloa sebaka le bohloeki.
- Netefatsa hore sehlahisoa sa ho qetela se fihlela maemo a indasteri le litlhoko tse ikhethileng tsa ts'ebeliso.
Qetello
Ho lokisoa ha li-ether tsa cellulose tsa Hydroxypropyl Methylcellulose (HPMC) tse hloekileng ho kenyelletsa letoto la mehato e laoloang ka hloko, ho tloha khethong ea thepa e tala ho isa taolong ea boleng ba ho qetela. Ka ho latela ts'ebetso ena e qaqileng, HPMC ea boleng bo holimo e ka hlahisoa, e loketseng mefuta e mengata ea lits'ebetso tsa indasteri. Tataiso ena e felletseng e fana ka temohisiso mabapi le mekhoa ea bohlokoa le lintho tse hlokoang bakeng sa tlhahiso e atlehileng ea HPMC.
